Synthesis of Tetra-Acetyl Ribofuranose by Sulfuric Ion Supported on Titanium Dioxide and Zirconium Dioxide
Zhao Jinglian,Wang Yunhai
(School of Environmental and Chemical Engineering,Xi'an Jiaotong University,Xi'an 710049,China)

Abstract: 1,2,3,5-Tetra-O-acetyl-β-D-ribofuranose was synthesized from inosine and acetic anhydride in the presence of sulfuric ion supported on titanium dioxide and zirconium dioxide. Sulfuric ion supported on titanium dioxide and zirconium dioxide were prepared by immersing titanium dioxide and zirconium dioxide in sulfuric acid, and then baked at a fixed temperature. The catalyst is a mixture of sulfuric ion on titanium and sulfuric ion on zirconium in a fixed weight-rate. The yield of 1,2,3,5-Tetra-O-acetyl-β-D-ribofuranose can reach up to 84.6% under certain reactive conditions.
Keywords: 1,2,3,5-Tetra-O-acetyl-β-D-ribofuranose;inosine;solid superacid;acetylation